Exosomes for ED Treatment: What Do They Suppose?

Exosomes are like highly specialized “worker bees” on the edge of a stem cell that deliver proteins, RNA, and most promisingly – mRNA, the protein manufacturer. These crucial biochemicals then force other cells to make proteins that repair cell damage in your penis.

Exosomes are so small and nimble; they can travel through your bloodstream, carrying multiple doses of platelets and proteins to your penile tissue by crossing barriers that whole cells have trouble crossing.

Exosomes are considered to be the nanoparticles released from our cells that contain important proteins, growth factors, genetic information, and messenger RNA which are used in direct cell-to-cell communication.

Through this communication, exosomes regulate many vital processes in the body such as blood vessel growth, appropriate inflammatory responses, immune system regulation, and cellular proliferation and differentiation!

They are also much more effective than stem cells because:

  • injecting only exosome vesicles and none of the cell DNA allows us to avoid the potential risk posed by stem cells;
  • 5 billion exosomes are delivered in one 5cc PRP vial, it’s much more than a number of stem cells per vial because it’s impossible to fit that many whole stem cells into a vial.

That’s why our sexual health specialists have been getting exponentially perfect results with exosome PRP therapy.

What is regenerative medicine and how is it different from other drugs?

Regenerative medicine is different from typical drugs – and potentially much more powerful.

Many drugs treat the symptoms of a problem, not the underlying cause. Erectile dysfunction after pelvic surgery, such as for prostate or colorectal cancer, appears to be caused by increased cell death (apoptosis) of corpus cavernosum smooth muscle cells (CCSMCs). This damage has been seen as always irreversible. Regenerative medicine would seek to reverse erectile dysfunction by replenishing the population of CCSMCs.

So regenerative medicine seeks to harness the body’s own regenerative capacity to heal the underlying causes of medical and other problems.

In erectile dysfunction (ED), researchers reported in 2019 that exosomes purified from mesenchymal stem cells treat ED in rats by inhibiting apoptosis in corpus cavernosum smooth muscle cells. A further report from the same research group showed that exosomes from human stem cells successfully treated ED in a diabetic rat model.

Are exosomes safe?

Biologists have utilized exosomes as a diagnostic and preventative tool for decades. When produced in Mesenchymal Stem Cells (MSCs), they’ve been shown to help reduce inflammation, the root cause of many autoimmune dysfunctions. They’ve also been clinically proven to help grow new blood vessels (angiogenesis) more efficiently than whole stem cells.

One of the most common causes of ED is diabetes, which can damage the blood supply to the penis and the nerves that control an erection. A study published in The Journal of Sexual Medicine last year demonstrated that stem cell-derived exosomes alleviate diabetic erectile dysfunction.

Another 2018 study demonstrated that erectile function caused by cavernous nerve injury (CNI) was significantly improved with MSC exosome treatment. It enhanced smooth muscle and collagen content while preventing cell death in the corpus cavernosum (the bulk of penis tissue).

Exosomes from stem cells are an emerging regenerative medicine that could disrupt the way age-related degeneration is treated, including problems such as cardiovascular disease, neurodegeneration, osteoporosis, and erectile dysfunction.

Exosome products do not contain stem cells, and therefore, do not contain genetic material (DNA) from someone else potentially reducing risks of side effects. As with any injection therapy, there is always a risk of bruising, swelling, infection, or discomfort. The side effects are often temporary and typically last less than 24 hours but may last up to three days.

Exosome Therapy for Men’s Performance

Exosomes have been found to contain over 1000 growth factors and are now being regarded as one of the purest forms of stem cell therapy. The stem cells in our body constantly interact with exosomes to regenerate tissue, reduce inflammation, and facilitate healing. Exosome therapy utilizes these critical intracellular messengers to restore aging tissue and stimulate cell repair.

Benefits of Exosome therapy:

  • stronger, longer-lasting erections;
  • increased sensitivity and orgasm;
  • improved frequency of erections;
  • reduced need for Viagra or Cialis;
  • lasting results;
  • no surgery, minimally invasive;
  • no potential risks posed by stem cells.

How is the therapy performed?

Exosome therapy is a natural treatment most often used in conjunction with platelet-rich plasma (PRP) therapy to restore healthy blood flow to the penis. The PRP and Exosomes are injected together to stimulate repair and restore function to the penis. A local anesthetic is used to ensure that the procedure is comfortable and pain-free. PRP will provide growth factors and nutrients for the exosome product which can help improve the outcomes and benefits of the therapy overall.

How are exosomes different from stem cells?

Exosomes are the communicators that carry some of the most important biochemical messages to cells. Stem cells are “blank” cells that have the potential to develop into many different types of other cells. While exosome products are derived from mesenchymal stem cells, they do not contain any stem cells and therefore it is believed that they do not pose the same risks often associated with stem cells.

Is exosome therapy right for me?

Similar to other regenerative medicine procedures such as platelet-rich plasma, the ideal patient is one who does not smoke, eats a low-inflammatory and minimally processed diet, exercises regularly, and has realistic expectations about their results.

This is primarily because these therapies rely on the healing capacity of the patient which is most often dependent on an individual’s overall health status. One of our doctors can help determine if you are a good candidate for exosome therapy and help you make the changes necessary to optimize the treatment’s effectiveness. In general, patients can enjoy results from a single procedure, although multiple appointments may be necessary for some patients.

When will I see results?

Exosome therapy can be a long-term option for men seeking improved symptoms of ED. The regenerative effect of exosomes takes place approximately 6-10 weeks after the procedure while most patients experience the full benefit of their treatment by the third or fourth month. The results typically last one year although the duration of benefit may also be dependent on your overall health status. A maintenance program will be discussed with a doctor to help ensure that you continue seeing your benefits long after treatment.

To get the replies to all of your additional questions, concerns, and doubts, don’t hesitate to contact us for a free consultation.